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The efficacy of oral itraconazole in the treatment of otomycosis accompanied by a perforated tympanic membrane

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Original Article

Author Details : Akash NR Nama*, Dhaval Bhojani, Sudhakar Vaidya

Volume : 6, Issue : 4, Year : 2023

Article Page : 104-107

https://doi.org/10.18231/j.ijoas.2023.024

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Abstract

Background: Managing otomycosis in patients with an existing tympanic membrane perforation can pose challenges. However, this study underscores the efficacy of oral itraconazole as a viable treatment option for such instances.
Materials and Methods: The research encompassed 34 individuals experiencing both otomycosis and a perforated tympanic membrane. These participants received a combination of oral itraconazole and antibiotic ear drops as treatment. Over a period of six weeks, their progress was monitored to assess the treatment's effectiveness and to observe any potential instances of recurrence.
Results: Out of the total 34 subjects examined in the study, 25 individuals achieved complete recovery after just one week of oral itraconazole treatment. Among the remaining 9 patients, 6 experienced a successful resolution of the condition following two weeks of therapy. For 3 patients, an extended treatment duration was required, and in a singular case, a recurrence of the condition was observed at the six-week mark.
Conclusion: Oral itraconazole treatment presents as an efficacious substitute for conventional approaches in addressing otomycosis accompanied by tympanic membrane perforation.

Keywords: Itraconazole, Aural fungal infection (otomycosis), Perforated tympanic membrane

How to cite : Nama A N, Bhojani D, Vaidya S, The efficacy of oral itraconazole in the treatment of otomycosis accompanied by a perforated tympanic membrane. J Otorhinolaryngol Allied Sci 2023;6(4):104-107

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