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- DOI 10.18231/j.ijoas.12933.1981990416
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CrossMark
- Citation
Quantitative assessment of maxillary sinus dimensions and volume in chronic rhinosinusitis with antrochoanal polyps: A case-control study
- Author Details:
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Amit Kumar
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Richi Sinha
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Mahesh Kumar
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Deepak Kumar
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Sarita Kumari Mishra *
Background: Chronic rhinosinusitis with nasal polyps (CRSwNP) is a common inflammatory condition (10% prevalence) characterized by a type 2 eosinophil-dominated inflammation. Anatomical factors that impair sinus drainage may contribute to disease, but the role of sinus volume in CRSwNP is unclear.
Objective: To determine whether reduced maxillary sinus volume is associated with chronic maxillary rhinosinusitis with antrochoanal polyps (ACPs).
Materials and Methods: In a prospective case-control study, 36 patients with unilateral ACP underwent nasal endoscopy and CT imaging. Maxillary sinus dimensions (anteroposterior, craniocaudal, mediolateral, and mid-axial width) were measured on CT, and sinus volume was calculated using PACS software. Each patient’s unaffected contralateral sinus served as the control. Paired t-tests compared case vs control measurements.
Results: Maxillary sinuses with ACPs had a smaller mean volume (21.1 vs 24.5 cm³) than control sides, a difference trending toward significance (p = 0.053). The mean anteroposterior length was significantly reduced in ACP sinuses (3.82 vs 4.09 cm, p = 0.010). Differences in craniocaudal height and maximum width were not significant (p > 0.05). The mid-sinus width was slightly smaller in cases (2.68 vs 2.88 cm, p = 0.055).
Conclusion: Maxillary sinuses affected by ACPs tended to be smaller, especially in the anteroposterior dimension, compared to healthy sinuses. This suggests a potential anatomical predisposition for ACP development, warranting confirmation in larger studies.
References
- Dennis SK, Lam K, Luong A. A review of classification schemes for chronic rhinosinusitis with nasal polyposis endotypes. Laryngoscope Investig Otolaryngol. 2016;1(5):130–4. DOI: 10.1002/lio2.32
[Google Scholar] - Orlandi RR, Kingdom TT, Hwang PH, Smith TL, Alt JA, Baroody FM. International Consensus Statement on Allergy and Rhinology: Rhinosinusitis. Int Forum Allergy Rhinol . 2016;6(S1): Doi: 10.1002/alr.21695
[Google Scholar] - Sedaghat AR. Chronic rhinosinusitis. Am Fam Physician. 2017;96(8):500–506.
- Fokkens W, Lund V, Hopkins C, Hellings P, Kern R, Reitsma S. et al.European Position Paper on Rhinosinusitis and Nasal Polyps
- Rhinology 2020;0(0):1-464. Doi: 10.4193/rhin20.600
[Google Scholar] - Van Zele T, Claeys S, Gevaert P, et al. Differentiation of chronic sinus diseases by measurement of inflammatory mediators. Allergy. 2006;61(11):1280–9.
- Plager DA, Kahl JC, Asmann YW, Nilson AE, Pallanch JF, Friedman O. Gene Transcription Changes in Asthmatic Chronic Rhinosinusitis with Nasal Polyps and Comparison to Those in Atopic Dermatitis. Plos One. 2010;5(7):e11450. Doi:
- 1371/journal.pone.0011450.
- Hamilos DL. Host-microbial interactions in patients with chronic rhinosinusitis. J allergy Clin Immunol. 2014;133(3):640-53.e4. doi:
- 1016/j.jaci.2013.06.049
- Fokkens W, Lund V, Mullol J, Bachert C, Alobid I, Baroody F. et al EPOS 2012: European position paper on rhinosinusitis and nasal polyps 2012. A summary for otorhinolaryngologists. Rhinology 2012;50(1):1-12. Doi: 10.4193/rhino12.000
[Google Scholar] - Bolger WE, Parsons DS, Butzin CA. Paranasal sinus bony anatomic variations and mucosal abnormalities: CT analysis for endoscopic sinus surgery. Laryngoscope 1991;101(1):56-64. Doi:
- 1288/00005537-199101000-00010.
- Kennedy DW, Zinreich SJ, Rosenbaum AE, Johns ME. Functional endoscopic sinus surgery. Theory and diagnostic evaluation. Arch Otolaryngol. 1985;111(9):576–82. DOI: 10.1001/archotol.1985.00800110054002
[Google Scholar] - Razavi M, Sharifishoshtari S, Shirafkan S, Baratvand B. The effect of anatomical variations of concha bullosa on maxillary sinus volume using cone beam CT. Onkol Radioter. 2023;17(10):1-3.
- Escamilla-Islas FA, Treviño-González JL, Martínez-Camarillo JM. Antrochoanal polyp: a literature update. J Otolaryngol Rhinol. 2018;4:049.
- Aksakal C, Kinis V, Gunerigok M, Goksu N. Antrochoanal polyp in children and adults: a comparative analysis of 83 cases. B-ENT. 2021;17(1):1–6.
- Khanal UP, Adhikari A, Humagain MP. A study on measurements of different dimensions of maxillary sinuses in adults using computed tomography. Nepalese J Radiol. 2018;8(2):8–12. DOI:10.3126/njr.v8i2.22974
[Google Scholar] - Prabhat M, Rai S, Kaur M, et al. Computed tomography based forensic gender determination by measuring the size and volume of the maxillary sinuses. J Forensic Dent Sci. 2016;8(1):40–6. DOI: 10.4103/0975-1475.176950
[Google Scholar] - Kanthem RK, Guttikonda VR, Yeluri S, Kumari G. Sex determination using maxillary sinus measurements in computed tomography scans. J Forensic Dent Sci. 2015;7(2):163–7. DOI: 10.4103/0975-1475.154595
[Google Scholar] - Bangi BB, Ginjupally U, Nadendla LK, Vadla B. 3D evaluation of maxillary sinus using computed tomography: a sexual dimorphic study. Int J Dent. 2017;2017:9017078. DOI: 10.1155/2017/9017078
[Google Scholar]
How to Cite This Article
Vancouver
Kumar A, Sinha R, Kumar M, Kumar D, Mishra SK. Quantitative assessment of maxillary sinus dimensions and volume in chronic rhinosinusitis with antrochoanal polyps: A case-control study [Internet]. J Otorhinolaryngol Allied Sci. 2025 [cited 2025 Oct 26];8(3):83-87. Available from: https://doi.org/10.18231/j.ijoas.12933.1981990416
APA
Kumar, A., Sinha, R., Kumar, M., Kumar, D., Mishra, S. K. (2025). Quantitative assessment of maxillary sinus dimensions and volume in chronic rhinosinusitis with antrochoanal polyps: A case-control study. J Otorhinolaryngol Allied Sci, 8(3), 83-87. https://doi.org/10.18231/j.ijoas.12933.1981990416
MLA
Kumar, Amit, Sinha, Richi, Kumar, Mahesh, Kumar, Deepak, Mishra, Sarita Kumari. "Quantitative assessment of maxillary sinus dimensions and volume in chronic rhinosinusitis with antrochoanal polyps: A case-control study." J Otorhinolaryngol Allied Sci, vol. 8, no. 3, 2025, pp. 83-87. https://doi.org/10.18231/j.ijoas.12933.1981990416
Chicago
Kumar, A., Sinha, R., Kumar, M., Kumar, D., Mishra, S. K.. "Quantitative assessment of maxillary sinus dimensions and volume in chronic rhinosinusitis with antrochoanal polyps: A case-control study." J Otorhinolaryngol Allied Sci 8, no. 3 (2025): 83-87. https://doi.org/10.18231/j.ijoas.12933.1981990416